IMITREX Injection is administered to treat any subsequent attacks. Use: For the acute treatment of cluster headache. What other drugs will affect sumatriptan? What are the ingredients in Imitrex Tablets?
If you have any questions about Imitrex spray, please talk with your doctor, pharmacist, or other health care provider. Take the Pen out of the Carrying Case. Know the medicines you take. Vagus nerve, since the headaches are immediately connected to the urge to have a bowel movement.
Do not touch the Blue Button until you have pressed the Pen firmly against your skin to give a dose. HT1 agonists. Discontinue IMITREX Injection if these disturbances occur. Morgan DR, Trimble M, McVeigh GE "Atrial fibrillation associated with sumatriptan. Studies 2 and 3 the onset of relief was less than 10 minutes. Headache relief, as defined by a reduction in pain from severe or moderately severe to mild or no headache, was achieved in 70% of the patients within 1 hour of a single 6-mg subcutaneous dose of Imitrex Injection. Approximately 82% and 65% of patients treated with IMITREX 6 mg had headache relief and were pain free within 2 hours, respectively.
Medicines to stop headaches aren't working well for you. There were no differences in relief rates at 60 minutes postdose for IMITREX Injection, whether or not prophylactic medications were used. You tend to get them at the same time each year, such as the spring or fall. Because of their seasonal nature, people often mistake for or business stress. Imitrex may cause serious side effects. See “What is the most important information I should know about Imitrex?
If you do not get any relief after your first tablet, do not take a second tablet without first talking with your healthcare provider. Do not dispose of your used sharps disposal container in your household trash unless your community guidelines permit this. Do not recycle your used sharps disposal container. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Prinzmetal variant all forms of myocardial infarction, and silent myocardial ischemia. Cerebrovascular syndromes include, but are not limited to, strokes of any type as well as transient ischemic attacks. IMITREX STATdose System, 6 mg, containing 1 IMITREX STATdose Pen, 2 prefilled single-dose syringe cartridges, and 1 carrying case NDC 0173-0479-00. Before injecting IMITREX, check with your doctor on acceptable injection sites and see the instructions inside the carton on discarding empty syringes and reloading an autoinjector device. IMITREX, 0% placebo and bronchospasm 1% IMITREX, 0% placebo. Is this headache different from your usual migraine attacks? Sit down. Gently blow your nose to clear the nasal passages. Keep your head in an upright position, gently close 1 nostril with your index finger, and breathe out gently through the mouth. With your other hand, hold the container with your thumb at the bottom and your index and middle finger on either side of the nozzle. Insert the nozzle into your open nostril about Â½ inch. Do not press the blue plunger yet.
Contact your doctor if you have more than four headaches in one month 30 days. Tell your doctor if this medicine seems to stop working as well in treating your migraine attacks. The risk of heart disease, liver disease, and high blood pressure increases with age. Older adults may be more sensitive to the side effects of this drug, especially increased blood pressure and heart problems. RxList is part of the WebMD Health Network. The opinions expressed in the WebMD User Reviews are solely those of the User, who may or may not have medical or scientific training, and do not represent the opinions of WebMD. These member reviews have not been reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other purpose except for compliance with our Terms and Conditions. Refer to storage information printed on the package. If your medicine has expired the expiration date is printed on the treatment pack throw it away as instructed. Do not throw away your autoinjector. Welch KM "Drug therapy of migraine. Imitrex. See the end of this leaflet for a complete list of ingredients in Imitrex. Imitrex tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Imitrex tablets with caution. Urogenital: Acute renal failure. Who should not take IMITREX? If your migraine symptoms go away and then come back, or if you have a partial response to the first dose, you may take a second dose as directed by your doctor. Wait at least 2 hours between doses. The frequency and time to use of these additional treatments were also determined. It is not known if Imitrex is safe and effective in children under 18 years of age. It helps to keep a daily diary about your headaches. Every day, simply note whether you got one, and if you did, what symptoms you had. It also helps to include information about what you had to eat or drink, what was going on that day in your life, and how you slept the night before. Never use more than your recommended dose. Overuse of migraine headache medicine can make headaches worse. Migraines: One type of drug, called triptans, is the mainstay of migraine treatment. They include eletriptan Relpax naratriptan Amerge rizatriptan Maxalt sumatriptan Imitrex, Zecuity zolmitriptan Zomig and others. probalan
Try these drugs first. Then close the lid. Important: The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, blogs, or WebMD Answers are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Another study of 125 patients concluded that panic-like symptoms may explain the chest pain and related side effects after sumatriptan administration in patients with high levels of anxiety. IMITREX is not used to treat other types of headaches such as hemiplegic that make you unable to move on one side of your body or basilar rare form of migraine with aura migraines. The vascular 5-HT 1 receptor subtype to which sumatriptan binds selectively, and through which it presumably exerts its antimigrainous effect, has been shown to be present on cranial arteries in both dog and primate, on the human basilar artery, and in the vasculature of the isolated dura mater of humans. In these tissues, sumatriptan activates this receptor to cause vasoconstriction, an action in humans correlating with the relief of migraine and cluster headache. In the anesthetized dog, sumatriptan selectively reduces the carotid arterial blood flow with little or no effect on arterial blood pressure or total peripheral resistance. In the cat, sumatriptan selectively constricts the carotid arteriovenous anastomoses while having little effect on blood flow or resistance in cerebral or extracerebral tissues. The maximum single recommended adult dose of IMITREX Injection is 6 mg injected subcutaneously. Controlled clinical trials have failed to show that clear benefit is associated with the administration of a second 6-mg dose in patients who have failed to respond to a first injection. Schoenen J, Bulcke J, Caekebeke J, Dehaene I, Dekeyser J, Hildebrand G, Joffroy A, Laloux P, Louis P, Monseu G, Pierre P, Vander "Self-treatment of acute migraine with subcutaneous sumatriptan using an auto-injector device - comparison with customary treatment in an open, longitudinal study. Luman W, Gray RS "Adverse reactions associated with sumatriptan. Overall, the frequency of adverse reactions reported in the trials of cluster headache was generally lower than in the migraine trials. Exceptions include reports of paresthesia 5% Imitrex Injection, 0% placebo nausea and vomiting 4% Imitrex Injection, 0% placebo and bronchospasm 1% Imitrex Injection, 0% placebo. If migraine returns after an initial dose of subcutaneous injection, additional oral doses may be given up to 100 mg orally per day, with at least a 2 hour interval between tablet doses. The plot was constructed with data from patients who either experienced relief or did not require request rescue medication within a period of 2 hours following treatment. As a consequence, the data in the plot are derived from only a subset of the 258 headaches treated rescue medication was required in 52 of the 127 placebo-treated headaches and 18 of the 131 sumatriptan-treated headaches. Naproxen is known as a nonsteroidal anti-inflammatory drug NSAID. It is used to relieve pain. Sumatriptan belongs to a class of drugs called triptans. ifon.info cilostazol
How often do you have them? Mild or flushing may occur. These effects are usually temporary and may disappear as your body adjusts to this product. If any of these effects persist or worsen, contact your doctor or promptly. Studies 2 and 3 the onset of relief was less than 10 minutes. By educating doctors to look for signs of skin sensitivity in migraine patients, they can instruct patients to take the drugs early and may be able to improve the effectiveness of these drugs. Endocrine and Metabolic: Infrequent was thirst. How should I take IMITREX? Reports of transient and permanent blindness and significant partial vision loss have been reported with the use of 5-HT 1 agonists. Since visual disorders may be part of a migraine attack, a causal relationship between these events and the use of 5-HT 1 agonists have not been clearly established.
Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death, have been reported within a few hours following the administration of 5-HT 1 agonists. Discontinue Imitrex Tablets if these disturbances occur. Imitrex Tablets are contraindicated in patients with Wolff-Parkinson-White syndrome or arrhythmias associated with other cardiac accessory conduction pathway disorders. Sumatriptan is a headache medicine that narrows blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. Store Imitrex tablets between 36 and 86 degrees F 2 and 30 degrees C. Store away from heat, moisture, and light. Do not freeze. Do not store at temperatures above 86 degrees F 30 degrees C. Do not store in the bathroom. Keep Imitrex tablets in the case provided. Throw away expired medicine as directed by your doctor the expiration date is printed on the treatment pack. Keep Imitrex tablets out of the reach of children and away from pets. Keep all away from children and pets. All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine. Gastrointestinal: Ischemic colitis with rectal bleeding see xerostomia. For these reasons, FAERS case reports cannot be used to calculate incidence or estimates of risk for a particular product or compare risks between products. Loi V, Lai M, Pisano MR, Delzompo M "Sumatriptan and panic-like symptoms. Store your medicine away from heat and light. Triptans narrow constrict vessels in the and relieve swelling. Triptans have other properties that may help treat symptoms. There were no statistically significant differences between the 50-mg and 100-mg dose groups in any trial. Cardiovascular: Abdominal aortic aneurysm, angina, atherosclerosis, cerebral ischemia, cerebrovascular lesion, heart block, peripheral cyanosis, phlebitis, thrombosis, and transient myocardial ischemia. IMITREX. Such reactions can be life threatening or fatal. In general, anaphylactic reactions to drugs are more likely to occur in individuals with a history of sensitivity to multiple allergens. Imitrex Injection is contraindicated in patients with a history of hypersensitivity reaction to IMITREX. can i order apetamin-p payment
The most successful ways to treat the pain are a shot of and breathing oxygen through a face mask for 20 minutes. Other drugs used for migraines called triptans may work. Prescription medicines based on the ergot and nasal spray might also help. The nerve that's affected, the trigeminal nerve, is responsible for sensations such as heat or pain in your face. Product Information. Imitrex sumatriptan. Open the Carrying Case lid. Some medical conditions may interact with Imitrex tablets. An extra patient leaflet is available with Imitrex spray. Talk to your pharmacist if you have questions about this information. IMITREX Injection, call your doctor immediately. abilify buy now visa usa
It is not known whether sumatriptan will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. Your name may need to be listed on a sumatriptan pregnancy registry. Phonophobia also occurred in more than 1% of patients but was more frequent on placebo. Plot also includes patients who had no response to the initial dose. Best of luck to you. This is a very scarey and painful problem. Postmarketing Experience With Sumatriptan: Serious cardiovascular events, some resulting in death, have been reported in association with the use of IMITREX Injection or IMITREX Tablets. The uncontrolled nature of postmarketing surveillance, however, makes it impossible to determine definitively the proportion of the reported cases that were actually caused by sumatriptan or to reliably assess causation in individual cases. On clinical grounds, the longer the latency between the administration of IMITREX and the onset of the clinical event, the less likely the association is to be causative. Accordingly, interest has focused on events beginning within 1 hour of the administration of IMITREX. Other Events Observed in the Clinical Development of IMITREX: The following adverse events occurred in clinical trials with IMITREX Tablets and IMITREX Nasal Spray. Because the reports include events observed in open and uncontrolled studies, the role of IMITREX in their causation cannot be reliably determined. All reported events are included except those already listed, those too general to be informative, and those not reasonably associated with the use of the drug.
Other Vasospasm-Related Events: Sumatriptan may cause vasospastic reactions other than coronary artery vasospasm. Both peripheral vascular ischemia and colonic ischemia with abdominal pain and bloody diarrhea have been reported. Very rare reports of transient and permanent blindness and significant partial vision loss have been reported with the use of sumatriptan. Visual disorders may also be part of a migraine attack. Hold the Pen by the ridges at the top. There are many headache remedies. Medications can ease your pain, but changing your lifestyle to control stress or avoid triggers works well, too, and may prevent you from getting headaches. What works for one person may not work for another, so work with your doctor to find the best remedy for you. How should I use sumatriptan? Imitrex spray may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Imitrex spray with caution. Visser WH, Devriend RHM, Jaspers NMWH, Ferrari MD "Sumatriptan in clinical practice: a 2-year review of 453 migraine patients. They are usually triggered after pain medicine has worn off, prompting you to take another dose. After a while, you get a whenever you stop taking the medicine. zoloft in sydney
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Imitrex Injection should continue for at least 10 hours or while symptoms or signs persist. The systematic approach described above is intended to reduce the likelihood that patients with unrecognized cardiovascular disease will be inadvertently exposed to sumatriptan. Open the lid of the Carrying Case. Lab tests, including heart function tests, may be performed while you use Imitrex spray. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. It is unknown if this drug passes into milk. Consult your doctor before -feeding. Take this medication by mouth with or without food as directed by your doctor, at the first sign of a migraine. The dosage is based on your medical condition and response to treatment. If there is no improvement in your symptoms, do not take more doses of this medication before talking to your doctor. If your symptoms are only partly relieved, or if your headache comes back, you may take another dose at least two hours after the first dose. Do not take more than 200 milligrams in a 24-hour period. Plot. Patients taking rescue medication were censored at 15 minutes. Pen and the Cartridge Pack when they are not being used. Non-Site Specific: Angioneurotic edema, cyanosis, death see temporal arteritis. Imitrex tablets should not be used to prevent or reduce the number of migraine headaches you have. If you have a headache that is different than your usual migraine headaches, check with your doctor before using Imitrex tablets. The pharmacokinetics of sumatriptan in the elderly mean age: 72 years, 2 males and 4 females and in subjects with migraine mean age: 38 years, 25 males and 155 females were similar to that in healthy male subjects mean age: 30 years. albenza
Use before you start to use the IMITREX STATdose System. CAD prior to receiving Imitrex Tablets. If there is evidence of CAD or coronary artery vasospasm, Imitrex Tablets are contraindicated. For patients with multiple cardiovascular risk factors who have a negative cardiovascular evaluation, consider administering the first dose of Imitrex Tablets in a medically supervised setting and performing an electrocardiogram ECG immediately following administration of Imitrex Tablets. For such patients, consider periodic cardiovascular evaluation in intermittent long-term users of Imitrex Tablets. All medicines may cause side effects, but many people have no, or minor, side effects. For women, at what time in your monthly cycle do they happen? IMITREX Nasal Spray sumatriptan nasal spray is generally well tolerated. Across all doses, most adverse reactions were mild and transient and did not lead to long-lasting effects. The incidence of adverse events in controlled clinical trials was not affected by gender, weight, or age of the patients; use of prophylactic medications; or presence of aura. There were insufficient data to assess the impact of race on the incidence of adverse events. Advise the patient to read the FDA-approved patient labeling Patient Information and Instructions for Use. Clinical trials of Imitrex Tablets did not include sufficient numbers of patients aged 65 and older to determine whether they respond differently from younger patients. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy. They work great if you have about four headaches per month, but for people with more you need a triptan. Imitrex is great for about two headaches per week, but anymore than that and you risk being like me. I am resistant to about everything. IMITREX STAT dose Pen. Some sumatriptan side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. The half-life of elimination of sumatriptan is about 2 hours see and therefore monitoring of patients after overdose with IMITREX Injection should continue while symptoms or signs persist, and for at least 10 hours. Drink plenty of fluids as directed by your doctor to prevent and tell your doctor right away if you have a change in the amount of urine. IMITREX in their causation cannot be reliably determined. All reported events are included except those already listed, those too general to be informative, and those not reasonably associated with the use of the drug. Know the medicines you take. Keep a list of them to show your healthcare provider or pharmacist when you get a new medicine. Six of these 8 patients had ECG changes consistent with transient ischemia, but without accompanying clinical symptoms or signs. Of these 8 patients, 4 had either findings suggestive of CAD or risk factors predictive of CAD prior to study enrollment.
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I” on one side and “25” on the other in blister packs of 9 tablets NDC 0173-0735-00. If you miss a dose of Imitrex spray and you still have a headache, follow your doctor's dosing instructions. Contact your doctor if you are unsure of what to do if you miss a dose. Do not use Imitrex spray more often than prescribed. Do not use 2 doses at once. The figure shows the probability over time of obtaining headache response no or mild pain following treatment with oral sumatriptan. The averages displayed are based on pooled data from the 3 clinical controlled trials providing evidence of efficacy.
Hepatic Impairment: The liver plays an important role in the presystemic clearance of orally administered sumatriptan. Accordingly, the bioavailability of sumatriptan following oral administration may be markedly increased in patients with liver disease. Have you had, or do you have, epilepsy or seizures? Sumatriptan may also be used for purposes not listed in this medication guide. What is the most important information I should know about Imitrex Statdose sumatriptan injection? Dachs R, Vitillo J "Angioedema associated with sumatriptan administration.
This drug should not be used for prophylaxis. If you are taking chewable tablets, chew the tablet thoroughly before swallowing. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. IMITREX passes into your breast milk and may harm your baby. Talk with your healthcare provider about the best way to feed your baby if you take IMITREX. Talk to your doctor for details.
It is not clear whether the problem is associated with the treatment of males or females or both. Remember, if you answered YES to any of the above questions, then discuss it with your doctor. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.